Abstract

To evaluate the time for recovery of the sense of smell in patients with CRSwNP who underwent Reboot surgery compared to patients undergoing ESS in a long-term follow-up study. Data were collected retrospectively from 168 patients with severe uncontrolled CRSwNP, who underwent revision surgery, either as Extended Endoscopic Sinus Surgery (Reboot, 140 patients) or as regular Endoscopic Sinus Surgery (ESS, 28 patients) between January 1, 2014, and December 31, 2015, aiming to compare the outcome of surgeries after 2years of follow-up. Sense of smell was scored as judged by the patient using scores 0 to 3 reflecting a percentage estimate of remaining smell. Smell improved similarly in the Reboot and ESS groups over the first 9months, which was maintained over 24months in the Reboot, but not the ESS group (p = 0.007 after 18months, p = 0.001 after 24months). Furthermore, polyp recurrence rates were significantly lower in the Reboot group. Reboot surgery significantly improved olfactory function and significantly reduced nasal polyp recurrence rates over 2years post-operatively. Therefore, Reboot should be considered for patients with uncontrolled severe CRSwNP, specifically when ESS failed, to offer long-term smell and a polyp-free status. 3b.

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