Abstract
Amendment of the interpretation of recently published size-exclusion chromatography data for Dishevelled-3 on Superdex 200 and Sephacryl S-400 has led to an increase in the estimated size of the supermolecular state from 2000 to 35 000 kDa, a value that essentially duplicates the redetermined and reported estimates obtained by fluorescence correlation spectroscopy on live cells. The earlier discrepancy between the sizes of the extensively aggregated form of this scaffold protein in vivo and in vitro is thereby eliminated.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
