Abstract
Aortic disease has a high rate of morbidity and mortality, and there are no documented screening methods to date. Yet biochemical research does show a significant link between soluble receptor for advanced glycation end-products (sRAGE) protein and cardiovascular disease. Therefore, it can be hypothesized that sRAGE plasma levels may help differentiate patients with aortic disease from the general population, which this paper will review and present.
Highlights
According to the latest data from the Centers for Disease Control and Prevention, approximately 13,000 people die annually in the United States of aortic aneurysms in various anatomic localizations, with almost 80% of these deaths among people 65 years and older
Biochemical research does show a significant link between soluble receptor for advanced glycation end-products protein and cardiovascular disease
It can be hypothesized that soluble receptor for advanced glycation end-products (sRAGE) plasma levels may help differentiate patients with aortic disease from the general population, which this paper will review and present
Summary
Reasons to Investigate the Soluble Receptor for Advanced Glycation End-Product (sRAGE) Pathway in Aortic Disease.
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