Abstract

BackgroundDrug misuse is an important clinical problem associated with a poorer outcome in patients who have a diagnosis of schizophrenia. Qualitative studies have rarely been used to elicit reasons for drug use in psychosis, but not in schizophrenia.MethodsSeventeen people with a diagnosis of schizophrenia and who had used street drugs were interviewed and asked to describe, in narrative form, their street drug use from their early experiences to the present day. Grounded theory was used to analyse the transcripts.ResultsWe identified five reasons for continuing street drug use. The reasons were: as an 'identity defining vocation', 'to belong to a peer group', due to 'hopelessness', because of 'beliefs about symptoms and how street drugs influence them' and viewing drugs as 'equivalent to taking psychotropic medication'. Street drugs were often used to reduce anxiety aroused by voice hearing. Some participants reported street drugs to focus their attention more on persecutory voices in the hope of outwitting their perceived persecutors.ConclusionsIt would be clinically useful to examine for the presence of the five factors in patients who have a diagnosis of schizophrenia and use street drugs, as this is likely to help the clinician to tailor management of substance misuse to the individual patient's beliefs.

Highlights

  • Drug misuse is an important clinical problem associated with a poorer outcome in patients who have a diagnosis of schizophrenia

  • Psychosocial factors appear to be important in maintaining substance use in this population [5,6,8,9] and a thorough assessment of psychosocial factors is important in engagement

  • Reasons for attempting to not use drugs were because of negative effects on mental state [16]; cost and illegality [16]; to improve health, finances and family relationships [15]. It remains unclear whether the results of qualitative studies of reasons for drug use in psychosis would be applicable to the narrower sub-group of people with schizophrenia; our study looks at reasons for drug use in schizophrenia

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Summary

Introduction

Drug misuse is an important clinical problem associated with a poorer outcome in patients who have a diagnosis of schizophrenia. A recent meta-analysis showed about 1 in 4 patients with schizophrenia had cannabis use disorder [2]. This is up to five times higher than in the general population [3] and results in higher rates of relapse, hospitalisation, suicide and other adverse outcomes [4]. The reasons for this comorbidity are complex and a number of competing theories have been generated and studied using quantitative methods [5,6,7,8]. Psychosocial factors appear to be important in maintaining substance use in this population [5,6,8,9] and a thorough assessment of psychosocial factors is important in engagement

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