Abstract
BackgroundWe used a large United States population-based database to analyze the reasons for hospitalization of psoriasis patients.MethodsInternational Classification of Diseases, 10th revision (ICD-10) code was used to identify hospitalizations in National Inpatient Sample (NIS) 2017 with a principal or secondary diagnosis of psoriasis. The reasons for hospitalization were divided into 19 categories based on their principal discharge ICD-10 diagnosis code. We also ranked the five most common specific reasons for hospitalization of psoriasis patients.ResultsThere were over 35 million discharges included in the 2017 NIS database. A total of 165215 hospitalizations had either a principal or secondary ICD 10 code for psoriasis. Based on ICD-10 code categories, the top five reasons for hospitalization in patients with history of psoriasis were: Cardiovascular (CV) (26605, 16.10%), rheumatologic (19555, 11.84%), digestive (18465, 11.18%), infection (16395, 9.92%), and respiratory (14865, 9.00%). Sepsis was the most common principal diagnosis of psoriasis hospitalizations.ConclusionCV diseases were the most common ICD category, and sepsis was the most common principal diagnosis for psoriasis hospitalization. Management of medical co-morbidities is important in reducing rates of hospitalization of psoriasis patients.
Highlights
Psoriasis is a chronic inflammatory autoimmune disorder of the skin affecting over 2% of the United States (US) population
There were over 35 million discharges included in the 2017 National Inpatient Sample (NIS) database
Psoriasis was thought to be a disease of the skin, it has become increasingly recognized as a systemic inflammatory disease resulting in multiple comorbidities, especially with longer duration and severity of the disease [3,4]
Summary
Psoriasis is a chronic inflammatory autoimmune disorder of the skin affecting over 2% of the US population. It increases incidence with age and frequency among Caucasians compared to other ethnic groups and no clear inclination towards gender [1,2]. Psoriasis was thought to be a disease of the skin, it has become increasingly recognized as a systemic inflammatory disease resulting in multiple comorbidities, especially with longer duration and severity of the disease [3,4]. The association of psoriasis with multiple comorbidities is thought to be due to shared genetics, pathophysiology of systemic inflammation, and the increased prevalence of risk factors like smoking, obesity, and alcohol use in psoriasis patients [11]. We used a large United States population-based database to analyze the reasons for hospitalization of psoriasis patients
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