Abstract
Lymph node dissection following lung metastasectomy is still debated, although it is considered necessary to achieve complete resection or at least gather prognostic information. When radical lymph node dissection is performed, the average rate of unexpected lymph node involvement in colorectal cancer is less than 20%. Lymph node co-involvement is an adverse prognostic factor, and preoperative mediastinal disease usually leads to patient exclusion from metastatic surgery. The authentic prognostic influence of systematic nodal dissection remains unclear. Unfortunately, many studies demonstrate no positive effect of lymphadenectomy during lung metastasectomy other than a pseudo-stage migration effect. Future studies should focus not only on survival but also on local and lymph node recurrence.
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