Abstract

We read with interest the article “Impaired Lung Function After Intubation and Mechanical Ventilation for Surgical Ligation of the Ductus Arteriosus in Preterm Infants” by Dzukou et al.1 Lung parenchymal damage during intermittent positive-pressure ventilation (IPPV) secondary to the activation of inflammatory cascades2 and an increase in permeability of the alveolar-capillary barrier and increased vascular transmural pressure have been described.3 The findings of this article are of far-reaching clinical importance and potentially change neonatal intensive care practice.

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