Abstract
Background In current practice, the diagnostic yield of endomyocardial biopsy is low because the procedure is performed ‘blind’ using X-ray fluoroscopy guidance and because many pathologies affect the myocardium in a patchy distribution. We hypothesized that biopsy performed under direct realtime MRI guidance would have superior diagnostic yield, in an animal model of focal myocardium pathology.
Highlights
In current practice, the diagnostic yield of endomyocardial biopsy is low because the procedure is performed ‘blind’ using X-ray fluoroscopy guidance and because many pathologies affect the myocardium in a patchy distribution
We hypothesized that biopsy performed under direct realtime MRI guidance would have superior diagnostic yield, in an animal model of focal myocardium pathology
A porcine model of focal myocardial pathology that enhances with late gadolinium enhancement imaging and that contained fluorescent tags that are identifiable under ultraviolet light was created
Summary
Real-time magnetic resonance imaging guidance improves the yield of endomyocardial biopsy. Toby Rogers1*, Kanishka Ratnayaka, Parag Karmarkar, William Schenke, Jonathan R Mazal, Adrienne E Campbell-Washburn, Ozgur Kocaturk, Anthony Z Faranesh, Robert J Lederman. From 19th Annual SCMR Scientific Sessions Los Angeles, CA, USA. From 19th Annual SCMR Scientific Sessions Los Angeles, CA, USA. 27-30 January 2016
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