Reallocating bouted sedentary time to non-bouted sedentary time, light activity and moderate-vigorous physical activity in adults with prediabetes and type 2 diabetes

Jenny Rossen,Barbara Ainsworth,Unn-Britt Johansson,Matthew P Buman,Maria Hagströmer,Kerstin Brismar,Agneta Yngve,Maciej Buchowski

doi:10.1371/journal.pone.0181053

Abstract

AimThe aim of this study was to investigate the potential associations of reallocating 30 minutes sedentary time in long bouts (>60 min) to sedentary time in non-bouts, light intensity physical activity (LPA) and moderate- to vigorous physical activity (MVPA) with cardiometabolic risk factors in a population diagnosed with prediabetes or type 2 diabetes.MethodsParticipants diagnosed with prediabetes and type 2 diabetes (n = 124, 50% men, mean [SD] age = 63.8 [7.5] years) were recruited to the physical activity intervention Sophia Step Study. For this study baseline data was used with a cross-sectional design. Time spent in sedentary behaviors in bouts (>60 min) and non-bouts (accrued in <60 min bouts) and physical activity was measured using the ActiGraph GT1M. Associations of reallocating bouted sedentary time to non-bouted sedentary time, LPA and MVPA with cardiometabolic risk factors were examined using an isotemporal substitution framework with linear regression models.ResultsReallocating 30 minutes sedentary time in bouts to MVPA was associated with lower waist circumference (b = -4.30 95% CI:-7.23, -1.38 cm), lower BMI (b = -1.46 95% CI:-2.60, -0.33 kg/m2) and higher HDL cholesterol levels (b = 0.11 95% CI: 0.02, 0.21 kg/m2. Similar associations were seen for reallocation of sedentary time in non-bouts to MVPA. Reallocating sedentary time in bouts to LPA was associated only with lower waist circumference.ConclusionReallocation of sedentary time in bouts as well as non-bouts to MVPA, but not to LPA, was beneficially associated with waist circumference, BMI and HDL cholesterol in individuals with prediabetes and type 2 diabetes. The results of this study confirm the importance of reallocation sedentary time to MVPA.

Highlights

Individuals with prediabetes and type 2 diabetes are recommended to engage in at least 150 min/week of moderate-to vigorous intensity physical activity (MVPA) [1]
Reallocating 30 minutes sedentary time in bouts to MVPA was associated with lower waist circumference (b = -4.30 95% CI:-7.23, -1.38 cm), lower BMI (b = -1.46 95% CI:-2.60, -0.33 kg/m2) and higher HDL cholesterol levels
The results of this study confirm the importance of reallocation sedentary time to MVPA

Summary

Introduction

Individuals with prediabetes and type 2 diabetes are recommended to engage in at least 150 min/week of moderate-to vigorous intensity physical activity (MVPA) [1]. Moderate intensity physical activity corresponds to repeated aerobic movement of large muscle groups such as walking, cycling, jogging and swimming (!3 Metabolic Equivalents) [1, 2]. These recommendations are based on rigorous evidence [1, 3]. Emerging evidence points at recommending interrupting SB alongside with being physically active This may be especially beneficial to people with impaired glucose tolerance [8,9,10]. To underpin such recommendations more evidence is needed in terms of how often breaks in SB should be accomplished [11] and what intensity should be promoted to substitute the sedentary time [11, 12]

Objectives

Methods

Conclusion