Abstract
Aim: To determine the effectiveness of bilayered living cellular construct (BLCC) versus a fetal bovine collagen dressing (FBCD) in pressure injuries (PRIs). Methods: A real-world data study was conducted on 1352 PRIs analyzed digitally. 1046 and 306 PRIs were treated with BLCC and FBCD, respectively. Results: Cox healing for BLCC (n=1046) was significantly greater (p<0.0001) at week 4 (13 vs 7%), 8 (29 vs 17%), 12 (42 vs 27%), 24 (64 vs 45%), and 36 (73 vs 56%). The probability of healing increased by 66%, (hazard ratio=1.66 [95% CI (1.38, 2.00)]; p<0.0001. Time to healing was 162days for FBCD and 103days for BLCC showing a 36% reduction in time to healing with BLCC; (p<0.0001). Conclusion: BLCC significantly improved healing of PRIs versus FBCD.
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