Real-time functional MRI feedback attenuates cue-induced craving in non-treatment-seeking nicotine-dependent smokers

Abstract

s / Drug and Alcohol Dependence 146 (2015) e202–e284 e229 Methods: Heroin addicts attending the syringe exchange of Malmo, Sweden, who are willing to participate, are referred to maintenance treatment and randomized to either a strength-based case management intervention in order to facilitate referral, or to referral-only. If eligible for treatment, patients are initiated on the maintenance treatment after 11 days. Study outcome is successful transfer from syringe exchange to treatment initiation. Results: After applying exclusion criteria, 79 heroin users at the syringe exchange programme were addressed and offered to participate in the study. 75 patients turned up for baseline interview and randomization and of those 74 that is 99% of included subjects showed up for medical assessment. Out of the total of 74 that showed up for medical assessment 71 (96%) successfully started treatment. After 6months 63patients remained in treatment (89%). Conclusions: Our data indicate that syringe exchange in a Swedish setting can be efficient for transferring heroin-dependent patients to evidence-based treatment. Strength-based case management intervention did not predict referral to treatment initiation. We also showed high retention rates at 6 months. Financial support: Skane region Swedish research council for health, working life and welfare. http://dx.doi.org/10.1016/j.drugalcdep.2014.09.089 Real-time functional MRI feedback attenuates cue-induced craving in non-treatment-seeking nicotine-dependent smokers Kathleen T. Brady1,2, Colleen A. Hanlon1, Karen Hartwell1,2, Jeffrey Borckardt1, James Prisciandaro1, Melanie Canterberry1, Xingbao Li1, Todd LeMatty1, Max Owens1, Michael E. Saladin1, Megan Moran-Santa Maria1, Mark George1,2 1 Psychiatry, Medical University of South Carolina, Charleston, SC, United States 2 Ralph H. Johnson VAMC, Charleston, SC, United