Reaktions‐ und verfahrenstechnische Aspekte der Heterogenisierung homogen‐katalysierter Synthesen

Abstract

AbstractReaction and process engineering aspects of transforming homogenous catalytic syntheses into heterogeneous processes. In order to avoid the separation of the catalyst in homogeneous catalytic processes, the preparation of supported phase catalysts has attracted widespread attention in recent years. Most interest has focussed on the immobilization of transition‐metal complexes on solid supports for catalyzing carbon monoxide and olefin reactions. After a survey of the development of solid supported phase (SSP)‐ and supported liquid phase (SLP)‐catalysts two reactions in which SSP‐catalysts have been applied are considered in detail: The carbonylation of methyl acetate to acetic anhydride and the stereoselective hydrogenation of 2‐acylaminocinnamic acid to (S)‐phenylalanine, a derivative of L‐DOPA. In order to discuss the favourable characteristics and the disadvantages of SSP‐catalysts, they are compared to soluble catalysts. Furthermore, the design of both processes is discussed.