Abstract
Reaffirming and Clarifying the American Society of Clinical Oncology's Policy Statement on the Critical Role of Phase I Trials in Cancer Research and Treatment.
Highlights
On behalf of ASCO, we thank Dr Jonathan Kimmelman for highlighting a number of important issues in the design and conduct of phase I clinical trials in oncology.[1]
The ethics surrounding cancer phase I trials have been an important topic of discussion throughout the modern history of clinical cancer research and continue to be important in the development of new drugs
The standard of care for patients who participate in phase I trials usually is either to forego anticancer treatment and pursue symptom management or to receive off-label cancer drugs with little proven effectiveness
Summary
Is participation in cancer phase I trials really therapeutic? 2. Weber JS, Levit LA, Adamson PC, et al: American Society of Clinical Oncology policy statement update: The critical role of phase I trials in cancer research and treatment.
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