Ready-set-go, a matter of fronto-central cortical negativity amplitude

Abstract

Event Abstract Back to Event Ready-set-go, a matter of fronto-central cortical negativity amplitude Isabel Cordones1*, Carlos Gomez1 and Miguel Escudero1 1 Universidad de Sevilla, Neurociencia y Comportamiento, Fac.de Biologia, Spain A contingent negative variation (CNV) develops during the preparation for an incoming task. Some variations on this slow negative potential occurs during a gap period (when the preparatory stimulus disappear indicating the imminence of the task), however the relationship between CNV and gap negativity remains poor understood. In the present study, eye movements and EEG activity were recorded on 8 healthy subjects during a prosaccadic/antisaccadic/no-go paradigm. Subjects seated in front of a CRT monitor fixed their gaze on a central color point (0.6 º) for a random period of 1500-2500 ms. Trials were mixed and the color of the fixation point was the key for the task on each trial. Color point disappeared for 300 ms and a peripheral black point appeared at 8º on right or left side, randomly. Required responses for prosaccade, antisaccade, and no-go trials, respectively, were to generate a saccade to the target, look away from it, and maintain the gaze on the center of the screen. During the gap period, the ERP showed a sudden increase in negativity that reached the maximum at the onset of the target. This negativity was higher for antisaccade, followed by prosaccade and no-go task (p<0.01). Inter-trial coherence analysis showed a synchronization on fronto-central regions at 3 Hz for pro- and antisaccade paradigms. When a two dipole solution was fitted to the gap period (-100 to 0 ms), the dipoles displayed similar positions for the three experimental conditions, one in the supplementary motor cortex and the other in subcortical structures. The current source density topography was also similar for the three conditions suggesting a brain source in the supplementary motor cortex. So, the gap-negativity shows topography similar to the CNV, suggesting that the gap-negativity is an intensification of preparation. The intensity of this preparation in supplementary motor cortex was related to the difficulty of the task. Conference: 41st European Brain and Behaviour Society Meeting, Rhodes Island, Greece, 13 Sep - 18 Sep, 2009. Presentation Type: Poster Presentation Topic: Poster presentations Citation: Cordones I, Gomez C and Escudero M (2009). Ready-set-go, a matter of fronto-central cortical negativity amplitude. Conference Abstract: 41st European Brain and Behaviour Society Meeting. doi: 10.3389/conf.neuro.08.2009.09.120 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 08 Jun 2009; Published Online: 08 Jun 2009. * Correspondence: Isabel Cordones, Universidad de Sevilla, Neurociencia y Comportamiento, Fac.de Biologia, Seville, Spain, mescudero@us.es Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Isabel Cordones Carlos Gomez Miguel Escudero Google Isabel Cordones Carlos Gomez Miguel Escudero Google Scholar Isabel Cordones Carlos Gomez Miguel Escudero PubMed Isabel Cordones Carlos Gomez Miguel Escudero Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.