Abstract
I read the article by Edén et al. regarding COVID-19 patients with neurologic symptoms with interest.1 It appears the adults with neurologic symptoms, primarily of encephalopathy, are similar to those of children with influenza experiencing encephalopathy—CSF neopterin elevation being a common feature, whereas CSF pleocytosis was only present in a third of patients.2 Influenza-related encephalopathy is believed to primarily be mediated through inflammatory or immune-mediated mechanisms.2
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