Abstract

Reactive oxygen species (ROS) play a key role in various physiological and pathological processes. Abnormally elevated ROS levels are generally related to the pathogenesis of inflammatory diseases and tumors. Real-time imaging and quantification of ROS can not only provide new insight into mechanistic understanding of diseases associated with ROS but also facilitate high-throughput and high-content drug screening for these diseases. Here, the present protocol introduces ROS-responsive and self-illuminating nanoparticles with chemiluminescence (CL) and fluorescence (FL) properties that can serve as an effective nanoprobe for imaging of pathophysiology, including inflammation and tumor.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call