Reactive lymphoid hyperplasia of the liver

Abstract

Reactive lymphoid hyperplasia (RLH) is a rare benign condition that forms a mass-like lesion characterized by proliferation of non-neoplastic lymphocytes forming follicles and germinal centers. RLH is thought to represent a reactive immunological response, and some cases may arise in association with malignancy and hepatitis.1 Radiologically, RLH of the liver may mimic a primary or metastatic hepatic malignancy. Therefore, it is very difficult to diagnose correctly without pathological examination. In this issue, we present a case of hepatic RLH and discuss the histopathologic findings with a review of the literatures.