Abstract
The extraction and reextraction of Penicillin G was investigated with different reactive components. The degrees E R of reextraction and E G extraction + reextraction were evaluated as a function of the pH value, carrier and penicillin concentrations. Besides Amberlite LA-2, nine different reactive components were tested and diisotridecylamine was found to be the most suitable one. The quaternary ammonium salt Adogen 464 is suitable also for the extraction of penicillin. However, the reextraction is incomplete. Therefore, sodium salt of p-toluene sulfonic acid was used as counter-ion, and it was regenerated by NaOH or Cl − anion. The advantages of the use of quaternary ammonium salts are discussed.
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