Reactions of n,n'-thiocarbonyl diimidazole with 1,3-dipolar agents : The synthesis of 5-substituted-2-(1-imidazolyl)-1,3,4-thiadiazoles and 5-( 1-imidazolyl)-1,2,3,4-thiatriazole

Abstract

By the reaction of N,N'-thiocarbonyl diimidazole with diazomethane, diazoacetic ethylester, phenyl diazoketone and 4-nitrophenyl diazomethyl ketone catalysed by tertiary amines, 5-substituted 2-(1-imidazolyl)-1,3,4-thiadiazoles were prepared, by the action of N,N'-thiocarbonyl diimidazole with azoimide, trimethylsilyl azide and thiophosgene 5-(1-imidazolyl)-1,2,3,4-thiatriazole was synthesised. The structure of compounds prepared was proved by 1H NMR and mass spectrometry.