Reaction of quinoxaline with benzopyridines in acetic anhydrides in the presence of Zn dust

Abstract

The reaction between quinoxaline and benzopyridine in acetic anhydride in the presence of zinc dust gives a quinoxaline anion and a benzopyridine N-acetyl radical, which recombine to give the previously unknown N-acetyl dihydrobenzo-pyridine derivative of 1,2-dihydroquinoxaline. Under these conditions, quinoxaline alone gives 1,4-diacetyl-1,4-dihydroquinoxaline and 1-acetyl-2-(1,2-dihydroquinoxalyl-2)-1,2-dihydroquinoxaline.