Abstract

Reaction of 2-(acylamino)malonic acids esters with chloroethynylphosphonates yielded 2-substituted (5 E / Z )-5-(dialkoxyphosphoryl)methylidene-2-oxazoline-4,4-dicarboxylates, isomers of which could be separated. Following reaction of hydrolysis and decarboxylation affords 2-substituted 5-(dialkoxyphosphoryl)methyl-1,3-oxazole-4-carboxylates.

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