Abstract
Summary1) Less than 15% of copper in crude bovine cerebrocuprein I (Cu content 0.15%) and in fraction I copper proteins from normal human brain reacted directly with sodium diethyldithiocarbamate. 2) In brains from 2 cases of hepatolenticular degeneration 29 to 45% of the fraction I copper reacted directly. This direct-reacting copper, amounting to more than 7.5 μg/g fresh tissue i.e. more than 20-fold the amount of direct-reacting copper in normal human fraction I, may represent copper bound to brain proteins which are normally copper-free.
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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