Abstract
3-Nitroquinoline was reacted with potassium cyanide in methanol at refluxing temperature to give 3-methoxycinchoninonitrile (I) and 1-aminoisoxazolo [3, 4-c] quinoline (II) in the yield of 62% and 30%, respectively. 3-Nitrocinchoninonitrile (III), which was prepared by the reaction of 3-nitroquinoline with potassium cyanide in the presence of potassium ferricyanide, was treated with potassium cyanide in methanol to from I, and III was converted into II by reduction with zinc dust and ammonium chloride.
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