Abstract
The sera of rabbits immunized by fractions containing nontype-specific group A streptococcal antigens, belonging to cell wall proteins, were studied by the indirect immunofluorescence method. Antibodies reacting with fibroblasts of the interstitial connective tissue of the human heart were found in the sera. On the basis of the results of absorption experiments it is postulated that a cross-reacting antigen common with an antigen of the fibroblasts is present in some hydrochloric acid extracts obtained from streptococci of groups A and C.
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