Abstract
Reaction of 19-hydroxycholest-4-en-3-one (1) with diethylaminosulfur trifluoride (DAST) in acetonitrile at reflux gave 10β-fluoro-5, 1-seco-5, 19-cyclocholest-4-en-3-one (2) in 60% yield. Analogous reaction of androstane derivatives afforded the corresponding bicyclo[4.4.1] compounds 6 and 8. Under milder reaction conditions, the diethylaminosulfnate 3 was secured in 20% yield from 1.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
