Abstract
AbstractA novel synthetic approach leading to 1‐(trifluoromethyl)furan derivatives is reported. 4‐Aryl‐1,1,1‐trifluorobut‐3‐en‐2‐one was iodinated and subsequently reduced to give the corresponding alcohol. The resultant iodo compound was then subjected to coupling with phenylacetylene to furnish an (E)‐3‐aryl‐2‐(2‐phenylethynyl)‐1‐(trifluoromethyl)allyl alcohol, which could be cyclized by means of AgOTf to furnish a 2‐(trifluoromethyl)furan in fair yield. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.