Abstract

1. The equilibrium constants of the reaction between streptomycin and benzylamines at different concentrations and pH values have been determined. 2. The formation of azomethine proceeded according to the general synthesis scheme with the formation of a polarographically inactive intermediate amino alcohol. 3. Compounds were formed from benzylamine and two streptomycin molecules of the dimethylol derivative type in acidic medium and in the presence of streptomycin. 4. At pH 9.5–10.0, it has been expedient to carry out the reaction with a benzylamine excess and with a temperature reduction toward the end of the reaction.

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