Abstract
Acetylcysteine (ACC) is a mucolytic, expectorant medicine with antioxidant, anti-inflammatory, anti-infective, radioprotective, pulmonary protective, anticarcinogenic and antitoxic effects. The review describes the examples of ACC application in radiation diagnostics and therapy for pharmacological radioprotection of the patient’s body and organs. ACC mitigates the negative effects of radiation therapy on the healing of a postoperative wound by reducing oxidative stress markers. ACC significantly reduces the x-ray density of breast tissue, that is, reduces the cancer risk. It has been proven that intravenous and oral administration of ACC prevents nephropathy caused by radiopaque agents. The clinical effectiveness of ACC in the treatment of acute and chronic neurological syndromes of radiation disease is assumed.
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