Abstract
Smell and taste alterations are very common in patients with COVID 19, even when we are in an asymptomatic phase of the disease, it is reported that up to 80 to 90% of patients present anosmia and ageusia as a cardinal symptom of the disease. In this manuscript we will mention the alterations and the mode of action of the Sars-cov-2 virus at the level of the nasal and buccal fossae, taking into account the alterations at the cellular level as a result of this, based on current evidence, remembering that it is still unknown. A lot about this disease and the way this virus works.
Highlights
COVID 19 is a disease caused by the Sars-cov-2 coronavirus
J Endocrinology and Disorders domain, this fusion domain is discovered after maturation of the spike protein by both ACE2 and transmembrane serine protease 2
Both proteins are expressed mostly in the upper part of the respiratory tract and the greatest amount of these proteins is found in the olfactory epithelium, where the support cells are responsible for expressing most of it
Summary
COVID 19 is a disease caused by the Sars-cov-2 coronavirus. Both the new virus and the disease were unknown before the outbreak in Wuhan, it produces flu-like symptoms, including fever, cough, dyspnea, myalgia and fatigue. Sudden loss of smell and taste has been observed [1]. In the list of symptoms in COVID-19, as already mentioned, a sudden loss of the sense of smell and taste has been identified, which at this time is recognized as a cardinal symptom that can be found even in the absence of the others. In this review we will describe the cellular mechanism by which the loss of smell and taste occurs, based on current hypotheses to explain the pathophysiology of anosmia and ageusia In the list of symptoms in COVID-19, as already mentioned, a sudden loss of the sense of smell and taste has been identified, which at this time is recognized as a cardinal symptom that can be found even in the absence of the others. common symptoms, such as fever, cough, and shortness of breath [3].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
