Abstract

Clinical work-up for suspected cardiac chest pain is resource intensive. Despite expectations, high-sensitivity cardiac troponin (hs-cTn) assays have not simplified decision making. The impact of recently validated rapid triage protocols including the 0/1-hour hs-cTn pathway and outcomes may be limited by the heterogeneity in interpreting troponin results by clinicians. Further, diversity in clinical presentations and short episodes of care contradict creating a self-learning health system.

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