Abstract
<strong>Background:</strong> A re-emergent tremor is suggested to be specific to Parkinson’s disease and although a tongue tremor has been reported in levosulpiride-induced parkinsonism (LIP), re-emergence has never been reported. <strong>Case Report:</strong> A 59-year-old female presented with a 3-month history of bradykinesia, 2-week history of right-leg tremor, and 10-day history of lip and tongue tremor. A review of the medication revealed a 15-month history of levosulpiride consumption. On examination, asymmetric bradykinesia, rigidity, rest tremor of the right leg, and re-emergent tongue tremor were observed. The parkinsonism subsided after levosulpiride was stopped. <strong>Discussion:</strong> This is the first report of re-emergent tongue tremor in LIP.
Highlights
Levosulpiride is a benzamide derivative that blocks both central and enteric D2 receptors; it is frequently used for treatment of dyspepsia and as a prokinetic.[1]
Re-emergent tongue tremors have been reported in association with Parkinson’s disease (PD),[4,5] and tongue tremor has been previously reported in levosulpiride-induced parkinsonism (LIP) there are no reports of re-emergence
We did not perform functional imaging to confirm druginduced parkinsonism, the complete and persistent resolution of tremor and parkinsonism in the OFF state causally implicates levosulpiride in this case
Summary
Shweta Prasad[1,2], Vikram V.
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