Rationale and Design of the Latin-American Registry of Peripheral Interventions: Insights From SOLACI Peripheral

Abstract

BackgroundChronic limb-threatening ischemia represents the most advanced stage of lower extremity peripheral artery disease (PAD); the improvement in revascularization strategies has successfully reduced the number of patients who were previously deemed untreatable. The aim of this manuscript was to provide an overview of the demographic and clinical characteristics of patients with lower-limb peripheral artery disease, as well as the procedural and technical aspects of peripheral endovascular interventions in Latin America. MethodsThe Latin-American Society of Interventional Cardiology peripheral registry is a prospective, multicenter, observational, and hospital-based registry of patients with lower-limb PAD, who are treated with endovascular interventions across Latin-American countries. ResultsA total of 1057 independent procedures (997 patients) were analyzed in this report. The most common clinical presentation was chronic limb-threatening ischemia (61.2%): an advanced stage of the disease was common, and the symptomatic classification was predominately Rutherford V (minor tissue loss) in 37.6%, followed by Rutherford III (severe claudication [30.9%]). Of the patients, 14.8% had previous amputations, 22.2% had previous endovascular revascularizations, and 5.9% had previous surgical revascularizations. Index endovascular procedures mainly treated femoral-popliteal and infrapopliteal regions. Disease extending across multiple vascular territories was common and 27.6% of patients underwent angioplasty of multiple regions during the same procedure. There was a high prevalence of cardiovascular risk factors and concomitant comorbidities: hypertension (84.5%), dyslipidemia 67.4%), diabetes mellitus (64.7%), myocardial infarction (17%), and stroke (8.4%). Major adverse events during hospitalization included death from any cause (1.3%), cardiovascular death (0.7 %), myocardial infarction (0.4%), stroke (0.1%), and BARC ≥3a bleeding (0.8%). ConclusionsReal-world data on lower-limb PAD in Latin-American countries will help us identify unmet needs and generate evidence-based recommendations to facilitate the development of more effective preventive and treatment strategies according to each country’s necessities and resources.