Abstract
There were presented results of clinical trials on β-adrenoblockers usage in patients with chronic heart failure (CHF) as well as data of own study on nebivolol efficacy and tolerability in 113 patients with ischemic heart disease, complicated with CHF. It is emphasized that therapy with β-adrenoblockers positively influences on cardiac hemodynamics and CHF symptoms, significantly reduces mortality risk and the frequency of hospitalizations. The usage of β-adrenoblockers is indicated in CHF of any stage. Efficacy of metoprolol, bisoprolol and carvedilol had been proven in CHF therapy. Nebivolol was effective in elderly patients with CHF.
Highlights
Rational choice of β-adrenoblockers in chronic heart failure therapy M.L
It is emphasized that therapy with βadrenoblockers positively influences on cardiac hemodynamics and chronic heart failure (CHF) symptoms, significantly reduces mortality risk and the frequency of hospitalizations
The usage of β-adrenoblockers is indicated in CHF of any stage
Summary
Rational choice of β-adrenoblockers in chronic heart failure therapy M.L. Maximov Moscow medical academy named after I.M. Что некоторые β-блокаторы (метопролол) вызывают "up"-регуляцию (увеличение количества) β-адренорецепторов миокарда при ХСН. Высказали предположение, согласно которому улучшению сократительной функции сердца должно предшествовать уменьшение уровня симпатического влияния на сердце, что может, отчасти, объяснять эффективность β-блокаторов при лечении хронической сердечной недостаточности.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
