Abstract
Premature progesterone rise during IVF stimulation reduces endometrial receptivity and is associated with decreased pregnancy rates following embryo transfer (ET). To our knowledge, no data exists regarding the appropriate ratio of hMG (which has 1:1 LH:FSH activity) to rFSH (which has FSH activity alone) to improve pregnancy outcomes. Our objective is to determine if an optimal ratio of hMG:rFSH can be identified that best predicts a reduced risk of elevated serum progesterone levels and change in progesterone (ΔP) during IVF stimulation, and to determine whether this ratio can also predict pregnancy outcomes following fresh ET.
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