Abstract
Tetracycline detection has been a great concern because of its overuse and difficulty in degrading. Here, a detection method with ratio fluorescence was developed by synthesizing Eu3+ doped nanocomposites with NH2-MIL-53(Al) nanosheets. After adding tetracycline, the fluorescence intensity at 616 nm characteristic emission peak of Eu3+ was sensitized by the antenna effect generated from coordinating Eu3+ with tetracycline, but the fluorescence of NH2-MIL-53(Al) at 433 nm was quenched by the fluorescence resonance energy transfer between the Eu3+-tetracycline composition and NH2-MIL-53(Al). Therefore, the efficient detection of tetracycline was achieved based on this change of ratio fluorescence signal. The experimental results show that Eu3+/NH2-MIL-53(Al) has excellent selectivity, a wider linear range and a lower detection limit for detecting tetracycline. This method can afford favorable ideas for developing advanced chemical and biological sensors.
Highlights
Tetracycline (TC) has been used to treat bacterial infections due to its excellent antibacterial properties and good therapeutic effects.[1,2,3] It is difficult to be degraded
The experimental results show that Eu3+/NH2-MIL-53(Al) has a relatively high selectivity, a wide linear range and a low detection limit for detecting tetracycline
The NH2-MIL-53(Al) nanosheets were characterized by TEM, Powder X-ray diffraction (PXRD), FT-IR and uorescence spectroscopy
Summary
Tetracycline (TC) has been used to treat bacterial infections due to its excellent antibacterial properties and good therapeutic effects.[1,2,3] It is difficult to be degraded. Novel uorescence detection methods based on the design of highly effective uorescence probes have caught widespread attention because of their obvious advantages, such as simple, sensitive, fast and easy operation with a lower cost. The MIL-type MOF composed of Al3+ and dicarboxylate ligand is stable to water and high temperature.[20,25,26,27] efficient sensors can be developed by using the advantages of the composite materials based on MOFs nanosheets. A novel ratio-type uorescence sensor based on the composite material of MOFs nanosheets (Eu3+/NH2-MIL53(Al)) was prepared and used for detecting tetracycline. The highly sensitive detection of tetracycline can be achieved by using these ratio uorescence signal change. The mechanism diagram of the ratio-type detection of tetracycline by Eu3+/NH2-MIL-53(Al) nanocomposite is shown in Scheme 1
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
