Abstract
Optic nerve hypoplasia (ONH), a leading causes of childhood blindness, is a congenital abnormality characterized by underdevelopment of one or both optic nerves. While it is often associated with hypothalamic-pituitary axis defects, the exact relationship between these abnormalities and the degree of ONH is not well established. For example, there is no clear consensus regarding further workup with brain imaging or endocrinology evaluation in the setting of unilateral ONH. The goal of this study is to understand the correlation of unilateral ONH with systemic findings.
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