Abstract
Micro and ultramicro techniques were used to study the rate of formation and osmolality of oviductal fluid in anesthetized 4-day cycling rats. The highest rate of production of oviductal fluid was found during proestrus (84 nl/minute) and estrus (81 nl/minute) with the rate decreasing to 56 nl/minute on Day 1 of diestrus and to 32 nl/minute on Day 2 of diestrus. The osmolality of plasma and oviductal fluid did not vary throughout the estrous cycle. There was a small though highly significant (p less than .005) difference between paired plasma and oviductal fluid osmolalities. The results suggest that oviductal fluid formation in the rat involves both secretory and reabsorptive processes.
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