Abstract
KIE events: Hydroxylations of fatty acids by cytochrome P450 119 Compound I display no intermolecular kinetic isotope effect (KIE) in buffer and increase in rate with increasing chain length (see graph). With glycerol, the rate of reaction of lauric acid increases, and the KIE is revealed. The mechanism involves reversible formation of an unreactive complex of a fatty acid with Compound I and its isomerization to a reactive one.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
