RATE AND CLASSIFICATION OF DISLIPIDEMIA IN PATIENTS WITH IMPURE NEPHROTIC SYNDROME

Abstract

AIMS: To determine the rate, level, classification of dislipidemia in impure nephrotic syndrome patients. Patients and method: 47 in-patients with impure nephrotic syndrome at Department of Nephrology – Hue Central Hospital, from March, 2014 to March, 2015. Assess rate of dislipidemia according to guidelines of Asia Pacific Association and Vietnam National Heart Association 1998. Assess level of dislipidemia by NCEP ATPIII (2001) and classify dislipidemia by Fredrickson’s criteria. Results :Mean concentration of CT: 11.53±4.59 mmol/L; TG: 4.21±3.68 mmol/L; LDL-C: 7.55±3.95 mmol/L; HDL-C: 1.78±0.70 mmol/L. 98% of patients have at least abnormal in 1 component of lipidemia. 75% of patients have dislipidemia in all of three components. 94% of patients have high-limit to high CT; 94% of patients have high-limit to high TG; 90% of patients have high-limit to high LDL-C; 11% of patients have low-level of HDL-C. Dislipidemia type II is very common (88%), therein type IIb is found in 75%; type IIa in 13% of cases. Conclusion: In patients with impure nephrotic syndrome, dislipidemia is very common, disorders are in high risk level. Many components of lipidemia are abnormal at the same time, type II is dominant. Key words: nephrotic syndrome, impure, lipidemia.