Abstract
Liver plasma membranes were isolated from normal and essential fatty acid (EFA) deficient rats. Membranes from deficient animals showed a considerably lower 5´-nucleotidase activity but there was no difference in the Mg2+-Na+-K+-adenosine triphosphatase activity between the normal and deficient membranes. The cholesterol content of EFA-deficient membranes was significantly lower than the normal membranes, whereas the amount of total lipids and phospholipids was unaltered. There was a marked decrease in the 18:2 and 20:4 and an increase in the 16:1, 18:1 and 20:3 fatty acids of the deficient membranes as compared with membranes from normal rats.
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