Abstract
Ras-related C3 botulinum toxin substrate (Rac1) is a small GTPase that monitors external signals and activates downstream cascades by transmitting information from membrane-bound receptors to exert its physiological and pathological effects. It is essential for regulating actin cytoskeleton polymerization, organization, function, and dynamics. Rac1 is a widely studied molecule, and its role in various brain disorders and diseases has been studied in rodent and vitro models. This review discusses the involvement of Rac1 in the pathophysiology of neurological diseases, its molecular pathway in different neurological diseases, and its beneficial and detrimental pathophysiological role in different cell-type and neurological disease phases.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
