Abstract
Rasmussen encephalitis (RE) is a unilateral hemispheric encephalitis whose main clinical features include refractory focal epilepsy or epilepsia partialis continua, hemiparesis, and progressive cognitive decline. Despite theautoimmune pathogenesis of RE, the only definitive therapeutic option is currently represented by surgery. This is a case of a 23-year-old women, with a background of partial epilepsy resistant to carbamazepine occurring every 3 or 4 months, which first imaging investigations never shown any plausible cause. The patient had neither history of prenatal disease. She presented to us within a 48 hours of partial, reversible hemiparesis and loss of consciousness. A brain computed tomography (CT) was performed showing a cortical hemiatrophy.
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