Rash in an Extremely Low Birth Weight Infant

Akers Stephen M,Yossuck Panitan,Barretto Greg A,Moffett Kathryn S,Mitchell Michelle L,Kiefer Autumn S

doi:10.23937/2469-5750/1510053

Abstract

Primary cutaneous aspergillosis (PCA) is one of several invasive fungal infections that have increased in incidence in the last four decades. We present a case of an extremely low birth weight infant born at 24 weeks gestation diagnosed with cutaneous aspergillosis, highlighting the risk factors and clinical findings associated with neonatal PCA. Additionally, we discuss use of serum galactomannan testing as well as combination amphotericin B and voriconazole therapy.

Highlights

A 24-week gestation male, birth weight 620 gram, was born to a 27-year-old mother by vaginal delivery secondary to placental abruption and preterm labor
Primary cutaneous aspergillosis (PCA) is one of several invasive fungal infections that have increased in incidence in the last four decades
We present a case of an extremely low birth weight infant born at 24 weeks gestation diagnosed with cutaneous aspergillosis, highlighting the risk factors and clinical findings associated with neonatal PCA

Summary

Introduction

A 24-week gestation male, birth weight 620 gram, was born to a 27-year-old mother by vaginal delivery secondary to placental abruption and preterm labor. We present a case of an extremely low birth weight infant born at 24 weeks gestation diagnosed with cutaneous aspergillosis, highlighting the risk factors and clinical findings associated with neonatal PCA. We discuss use of serum galactomannan testing as well as combination amphotericin B and voriconazole therapy.

Results

Conclusion