Abstract

Leiomyosarcoma, an uncommon tumor, becomes even rarer when it emerges within the thyroid gland. Diagnosing it accurately is a challenging task due to its atypical location, diverse clinical and radiological presentations, its rarity, and overlapping differential diagnoses. However, immunohistochemistry studies can offer a precise identification. In this article, we present a compelling case of recurrent primary leiomyosarcoma of the thyroid gland in a 23-year-old man, revealed by inspiratory dyspnea caused by a voluminous cervical mass and ultimately confirmed as leiomyosarcoma through histopathological examination.

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