Rare lytic lesions of bone at uncommon locations-A study of 12 cases

Abstract

Introduction: Pathological lesions in skeletal system can be viewed radiologically as lytic lesions of bone. They can be either inflammatory conditions or neoplastic lesions. If they are neoplastic it can be again either benign or malignant. On radiological examination the nature of the disease cannot be assessed. Histopathology is the ultimate tool for the final diagnosis of such conditions. Aims and objectives: The main aim is to study the different lytic bone lesions, uncommon locations at which they can occur and the histopathological features of the same. Materials and Methods: This study was done at Mahadevappa Rampure Medical College from June 2017 to June 2018. A total of 12 bone lesions were analysed. Different investigations were done in different cases after radiological examination. The procedures done were fine needle aspiration cytology, bone biopsy and bone excision. Once they were done the specimens were taken for processing and the staining was done. After that histopathological diagnosis was made. Results: This study included a total number of 12 cases out of which 6 cases (50%) are between 25 – 50 years of age. Female predominance was observed. The incidence of non-neoplastic lesions was 8.3% and of neoplastic lesions was 91.67%. In the neoplastic lesions, the benign lesions were 25%, malignant tumours were 41.67% and metastatic tumours were 25%. Solitary plasmacytoma was most common tumour among malignant tumours. Also secondary metastasis was common among the malignant bone tumours. Conclusion: Bone tumours are not routinely found in clinical practice. If the presentation is at rare site it is difficult to come to a diagnosis. Though clinical and radiological approach is available, the histopathology can make the correct diagnosis. Keywords: Lytic bone lesions, Uncommon location, Histopathology.