Rare Localizations of Mesothelioma

Abstract

Malignant mesothelioma (MM) commonly occurs in the pleura and peritoneum but also arises rarely from the mesothelial cells at other anatomical sites, such as pericardium, Glisson’s capsule, and tunica vaginalis testis (TVT). These rare localizations of MM account for less than 1% of all MMs. Due to the rarity of these malignancies, it is difficult to obtain specific information about their incidence, natural history, and pathogenesis. An etiological role of asbestos exposure has been hypothesized but its association with these rare MM localizations is still discussed because of the absence of analytical case-control epidemiological studies.