Abstract

Rare-earth scintillating materials have been widely utilized in nuclear image technique, security screening and high energy physics research. Researchers have devoted extensive efforts to size design, surface modification, and drug assembly to transform them into prospective nanomaterials for diagnostics and cancer treatment. This review endeavors to summarize the advanced preparation technology and design concept of rare-earth nanocrystalline scintillators (RENSs), and offers fundamental guidance for the application of various materials in biomedical research. Specifically, it focuses on RENSs with excellent biocompatibility, outstanding stability, uniform size distribution, and strong drug loading capacity to meet subsequent practical applications. Additionally, this review reports on the application of RENSs in the biomedical field. Specifically, bioimaging and antitumor therapy are the most prevalently utilized and promising areas. X-ray excited optical imaging (XEOL) is combined with advanced imaging techniques (CT, MRI, etc.) to obtain comprehensive information about deep tissue. The combination of X-ray radiation therapy and photodynamic therapy technology can realize safe anti-tumor therapy under the condition of low-dose irradiation. Furthermore, this review also enumerates several recent highlight research strategies and the prospects of RENSs in the biomedical application in the future.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.