Rare childhood disease: Gorham-Stout syndrome

Abstract

Gorham-Stout syndrome is a rare disorder characterized by endothelial proliferation of vascular vessels that results in the development of destruction and resorption of osseous matrix. A 6-year-old girl admitted to hospital with fever and cough. Lytic bone lesions were detected on ribs chest radiograms, and humerus within region of examination. In medical history we learned that right humerus and both of clavicles were broken before when she was 3 years of age at different times from each other with minor traumas. Extensive lytic lesions were observed on radiograms of pelvis, cranium, upper and lower extremities. Magnetic resonance imaging of the patient’s extremities were consistent with Gorham-Stout disease. We presented this case because Gorham-Stout disease is a rare disease and the diagnosis is difficult at its onset, and the disease can easily be confused with other diseases.