Abstract

Infectious mononucleosis (MI) is caused by the Herpes viridae family of viruses. Currently, most researchers assign a leading role to the Epstein-Barr virus. In present time there are no unified clinical classification of infection mononucleosis, but many authors recognize the visceral form which involves cardiovascular system, adrenal glands, lungs, central neural system and others organs. The article describes a clinical case of MI in the 28-year-old patient. She applied for medical help with complaints of fever up to 39 °C, weakness in the legs and arms, weight loss and received symptomatic treatment on an outpatient department. After 2 months on the background of deterioration, she was hospitalized in an infectious diseases hospital with severe symptoms of intoxication, lymphoproliferative syndrome, myocarditis, pericarditis, hepatitis, polyneuropathy with quadriparesis, hypochromic anemia, thrombocytopenia. She was consulted by an oncologist and diagnosed with cervical cancer. Laboratory confirmation was obtained – Epstein-Barr virus was detected in the blood. Against the background of antiviral therapy, a regression of clinical symptoms was achieved in a week. The patient was transferred to a oncological hospital. It is recommended to examine patients with high fever of unknown etiology on myocardial infarction for the timely appointed etiotropic therapy.

Highlights

  • Инфекционный мононуклеоз (ИМ) вызывается большинство исследователей отводят ведущую роль вирусами семейства Herpes viridae

  • Krupka JA, Samelska K, Tomasik A, Stelmaszczyk-Emmel A, Pawelec K. (2017) Infectious mononucleosis-like syndrome with high lymphocytosis and positive IgM EBV and CMV antibodies in a three-year-old girl

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Summary

Introduction

Инфекционный мононуклеоз (ИМ) вызывается большинство исследователей отводят ведущую роль вирусами семейства Herpes viridae. В настоящее время вирусу Эпштейна – Барр (ВЭБ), но доказана этиоло- Около 90 % населения земного шара в возрасте старше 40 лет инфицированы ВЭБ. Около 50 % населения переносят инфекцию в подростковом возрасте (14–18 лет) [7, 8]. В настоящее время не существует единой клинической классификации ИМ, но многие авторы признают висцеральную форму как тяжёлое атипичное течение, когда в инфекционный процесс вовлекаются сердечно-сосудистая система, надпочечники, лёгкие, центральная нервная система и другие жизненно важные органы [4, 6, 8, 13].

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