Abstract
Solitary plasmacytoma of bone without signs of multiple myeloma is a rare entity. It usually presents as an osteolytic lesion in the axial skeleton of an elderly patient. Here, we report a case of solitary plasmacytoma in the skull of a young male patient which emphasises the need to consider it in the differential diagnosis of a destructive calvarial mass lesion even in this age group.
Highlights
Plasma cell neoplasms are a group of disorders characterised by the neoplastic proliferation of a single clone of plasma cells
Solitary plasmacytoma of bone (SPB) known as osseous plasmacytoma is a rare form constituting less than 5% of all cases of plasma cell disorders
Non-contrast computed tomography (NCCT) revealed a well-defined heterogeneous hyperdense mass lesion centred on the left parietal bone causing bone destruction, compressing the adjacent brain parenchyma and bulging into the scalp
Summary
Plasma cell neoplasms are a group of disorders characterised by the neoplastic proliferation of a single clone of plasma cells. It presents at the median age of 55 years.[1] Being the disease of older adults, the occurrence of SPB in a young individual is extremely rare, with only about 1.1% of cases occurring in individuals younger than 30 years of age.[2] We would like to report such a case of SPB in the skull of a young male patient. X-rays of the skull showed a well-defined lytic lesion in the left parietal bone with an associated large soft tissue component.
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